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Scientists build mini stomachs in lab

PARIS - Scientists using stem cells said they had built the world’s first ‘mini-stomachs’ - tiny clusters of human gastric tissue that could spur research into cancer, ulcers and diabetes. Called gastric organoids, the lab-dish tissue comprises buds of cells that are ‘a miniature version of the stomach’, the researchers said. They were made from pluripotent stem cells which were coaxed into developing into gastric cells, according to the study, published in the journal Nature. Youthful and versatile, pluripotent stem cells have excited huge interest as a dreamed-of source for transplant tissue grown in a lab. Sources for them include stem cells derived from early-stage embryos and adult cells reprogrammed to their juvenile state, called induced pluripotent stem cells (iPS).

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