US Secretary of State Hillary Clinton has said the Obama Administration will not enter into any agreement with Pakistan that would be to the detriment of the national security of the country. Replying to a question in an interview after visit to Middle East, Clinton said President Obama has demonstrated conclusively that he is ready to take the tough decisions when America's security is at stake. Clinton refused to comment when asked if US is going to agree to a different way of using drones which is a very controversial issue in Pakistan.