WASHINGTON (Agencies) The CIA on Tuesday said that American efforts both in Afghanistan and Pakistan were aimed at hitting command and control centres of the Al-Qaeda and Taliban. The CIA said counterterr-orism operations by the US have placed Al-Qaeda and Talibans top leaders under extreme pressure in Pakistan and Afghanistan and many are on the run due to this pressure on them. CIA Director Leon Panetta also warned India and Brazil that they face emerging threats from Al-Qaeda and Taliban, though the terrorist outfits are on the run due to extreme pressure exerted on them in Afghanistan and Pakistan. He said that the US spy agency has a fundamental duty to provide warning and prevent surprise, which also refers to emerging threats to nations like Brazil and India, indicating the need for growing cooperation between the US and India on intelligence sharing. Intense operations have put top Al-Qaeda and Taliban leaders under extreme pressure and many of them are on the run, Panetta claimed. He said, Our counter-terrorism operations have put top Al-Qaeda leaders under intense pressure and much of their network has been disrupted. Panettas claim comes as Pakistani forces with the help of CIA have captured some top Taliban commanders, including the groups No 2 Mulla Abdul Ghani Baradar. Without referring to covert drone attacks believed to be launched from Pakistani soil, Panetta said in his address at the University of Oklahoma that US was at war with Al-Qaeda and its affiliated terrorist organisations, claiming that operations in tribal areas of Pakistan, which were once considered an Al-Qaeda safe haven, have killed more than half of Al-Qaedas top 20 commanders. US drone attacks have also claimed to have killed more than 600 Al-Qaeda and Taliban militants in less than three years. Warning that it was a war, the US spy chief said that Al-Qaeda would keep on coming at the Americans, adding that new intelligence indicated that Osama bin Laden-led outfit was changing its tactics and trying to launch attacks on the US through people with no history of terrorist activities. In Afghanistan and Pakistan, Panetta said Americas goal is to degrade the Taliban in order to allow the Afghan people to govern themselves freely. The question that most concerned Panetta was whether the US would be able to ultimately transfer power to the Afghan people. The answer, he said, lies in whether the Karzai administration will succeed in building effective government, which he defined as the capacity to protect the people at the provincial level. Panetta said fighting the spread of deadly weapons is a core issue of the CIAs duties, especially in light of Osama bin Laden describing the acquisition of nuclear weapons a religious duty. The CIA Director said that the US is lagging behind in the cyber war and told the audience that he feared that the next Pearl Harbour might be a cyber attack. Panetta said four people who the CIA did not know were arrested in the US last year including admitted Al-Qaeda associate Najibullah Zazi, a Colorado airport van driver who pleaded guilty last month to terror charges. My worry is there are others that have been deployed here that we dont know about, Panetta said. Al-Qaeda is also turning to individuals who are not trained terrorists and have no history of terrorism including the Nigerian man accused in the failed Christmas Day bombing of a Detroit-bound airliner. Panetta said individuals with no documented link to terrorist activity are much more difficult to try to pin down. He said another new form of terrorist threat is the lone wolf who becomes self-radicalised and decides on his own to take violent action without Al-Qaeda taking a direct role. Panetta cited the case of Maj Nidal Hasan, an Army psychiatrist who is charged with killing 13 people in the Nov 5 shooting spree at Fort Hood. We constantly have to adjust our tactics and capabilities in this fight, Panetta said.