WASHINGTON - Two Pakistani origin men - Tahawwur Rana and David Headley - both from the Chicago area, were indicted Thursday on charges of helping terrorist plot to kill a Danish cartoonist who depicted Prophet Muhammad (PBUH). Rana is now also accused of aiding the terrorists who planned the November 2008 Mumbai attacks that killed 164 people over three days. Headley, a US citizen who was previously charged in connection with that assault, pleaded not guilty on Dec 9 before US District Judge Harry Leinenweber in Chicago. Six Americans were killed in that siege, the US Justice Department said in a statement Thursday announcing the 12-count federal grand jury indictment. Rana, a Canadian citizen, and Headley have known each other since attending the Cadet College in Hasan Abdal in the entry class of 1974. Newly charged is Ilyas Kashmiri, who prosecutors said is an allegedly influential terrorist organisation leader in Pakistan with ties to al-Qaeda. He and a fourth man, retired Pakistani military officer Abdur Rehman Hashim Syed, are alleged to have conspired in the Denmark attack plan. Rana and Headley, both 49, in October were accused of helping to plan an assault on Morgenavisen Jyllands-Posten, the Danish newspaper that published cartoons of the Prophet Muhammad (PBUH) in 2005. That attack wasnt carried out. The cases against Rana and Headley were initially filed separately in October. Both men are being held without bail. The other two men are not in custody, the US said. Ranas attorney, Patrick Blegen, has previously said his client is innocent. Blegen said by phone today that he couldnt immediately comment on the new charges. No arraignment date has been set. Prosecutors and Headleys lawyer, John Theis, have said his client is cooperating with the governments probe. I would expect that at the arraignment he will be entering a plea of not guilty, Theis said. Rana, who was arrested at his home on Oct 18, was the operator of an immigration services business with offices in Chicago, New York and Toronto. Rana, according to prosecutors, used his business to aid Headley as he scouted targets in Mumbai and, later, in Copenhagen. A US citizen who is the son of an American mother and Pakistani father, Headley was born Daood Gilani. He changed his name in 2006 to disguise his parentage before making a reconnaissance trip to India that year, prosecutors have said.