CAIRO - At least six people were killed on Friday in clashes between pro- Muslim Brotherhood protesters and Egyptian police in Cairo, the health ministry said.

Supporters of ousted Islamist president Mohamed Morsi had held small marches after the morning prayers for Eid al-Fitr, which marks the end of the holy Muslim fasting month of Ramadan. Police officials said the protesters attacked security forces stationed in Cairo’s Talbiya district near the Giza pyramids. The health ministry did not give a breakdown of those killed.

Protest clashes were also reported in the village of Nahya near Cairo. In the Mediterranean city of Alexandria, police arrested 20 Islamist protesters after they directed fireworks at policemen, the official MENA news agency reported.

Pro-Morsi protests have dwindled since his ouster by the military in 2013, which led to a massive crackdown on Islamists that killed at least 1,400 people in street violence. Hardcore supporters continue to hold small protests that are often confined to one or two Cairo neighbourhoods. Demonstrations have largely given way to militant attacks, often small bombings and attacks on infrastructure such as electricity towers. In the Sinai Peninsula, jihadists affiliated to the Islamic State group have killed hundreds of policemen and soldiers in an insurgency since Morsi’s overthrow.

Morsi’s Muslim Brotherhood has been blacklisted and thousands of its sympathisers have been jailed. Hundreds, including Morsi, have been sentenced to death. Most have appealed the verdicts and won retrials. Protesters risk jail even for non violent demonstrations under a law that requires obtaining a police permit to demonstrate.

The crackdown has gutted the Muslim Brotherhood , once Egypt’s largest political movement. The Islamists had been banned for decades until a popular 2011 uprising ousted veteran strongman Hosni Mubarak. The went on to dominate parliament and then win the 2012 presidential election with their candidate Morsi, who lasted only a year in office.

The Islamist proved to be a divisive leader, prompting millions to demonstrate against him demanding his resignation. The crackdown on the Brotherhood has shown no signs of letting up, with weekly arrests of the group’s remaining organisers in Egypt. Many of the group’s leaders had fled the country and operate out of Turkey and the United Kingdom. Earlier this month, police killed nine mid-level and senior members of the Brotherhood in a raid on an apartment in Cairo as they were holding a meeting.

Police say they came under fire when they tried to arrest the men. Moreover, The Islamic State jihadist group said it carried out a missile attack on an Egyptian navy vessel off North Sinai on Thursday, the first such incident in a two-year insurgency. The group’s Egyptian affiliate claimed it fired a “guided missile” at the patrol boat north of Rafah, which neighbours the Gaza Strip, in a statement posted on one of its social media accounts.

It posted three pictures showing what appeared to be a guided anti-tank missile striking the vessel and causing a large fireball. The military had earlier said one of its boats came under attack and was set on fire while pursuing militants, but that it suffered no losses.

Other navy boats rescued the crew as their vessel spewed a plume of smoke, said an AFP photographer across the border in the Gaza Strip. They boarded the vessel, which stayed afloat, to extinguish the flames. Jihadists loyal to the Islamic State group have killed scores of Egyptian soldiers and policemen in the Sinai Peninsula since the army’s overthrow of Islamist president Mohamed Morsi in 2013.

The militants have also carried out attacks west of the Suez Canal, which separates the Sinai from the rest of Egypt. The army said on Wednesday its troops foiled a suicide car bombing of a military post between Cairo and Suez that was claimed by IS’s affiliate in Egypt.

Thursday’s attack, if confirmed, could be the Sunni extremist group’s first maritime attack. In November 2014, the Egyptian military said eight navy men drowned after one of its patrol boats came under attack off the country’s northern coast. But it has released no further details. The jihadists in Egypt have carried out a series of brazen attacks despite a massive crackdown by the army which says it has killed more than 1,100 militants in Sinai since Morsi’s overthrow.

The jihadists in Sinai, who pledged loyalty to IS in November, struck a series of military outposts and checkpoints on July 1 that killed at least 21 soldiers. They also claimed responsibility for a car bomb attack on the Italian consulate in Cairo last week. The bombing occurred in the early morning, when the consulate was closed, and killed an Egyptian civilian.

The government on Thursday sacked the police chief in Cairo following that and other attacks in the capital. Last month, the country’s top prosecutor was killed in a car bombing on his way to work in the city, prompting a furious President Abdel Fattah al-Sisi to pledge tougher anti-terrorism laws.

Sisi, the former army chief who toppled Morsi, had won elections in 2014 pledging to stamp out militant Islamists. Since Morsi’s overthrow, at least 1,400 people, mostly Islamists, have been killed in a police crackdown on protests. Thousands have been imprisoned and hundreds sentenced to death, including Morsi himself. Most of them have won retrials.