JERUSALEM (AFP/Reuters) - Hundreds of people, mostly left-wing Israeli activists, demonstrated against Jewish settlements in East Jerusalem on Friday in defiance of police efforts to crack down on the weekly protests. The gathering, modelled on regular Palestinian demonstrations in the occupied West Bank, was to protest the takeover of several Arab homes in the Sheikh Jarrah neighbourhood by settler groups armed with court orders. There is nothing holy about an occupied city, the demonstrators chanted in Hebrew, as several people held signs comparing the Israeli occupation to Apartheid South Africa. Scuffles broke out as police ordered the protesters to disperse, saying organisers had failed to get a permit for the gathering. Police detained 10 people, a spokesman said. Shortly thereafter fighting broke out as Palestinian protesters and a group of ultra-Orthodox Jews who had come to pray at a nearby holy site began throwing rocks at each other, an AFP photographer said. The photographer saw three Palestinians being taken away in ambulances, and police said at least one Jewish man was wounded. Meanwhile, in the West Bank town of Nabi Saleh, hundreds of Palestinians clashed with Israeli forces as they held a third weekly demonstration against Jewish settlements and Israels controversial separation barrier. Israeli forces arrested several people, including women, as Palestinians hurled rocks and the army responded with teargas and rubber bullets, according to an AFP photographer. Meanwhile, the US told Palestinian leaders on Friday they must resume talks with the Israelis if they want US help to achieve a peace treaty that ends Israeli occupation and creates a Palestinian state. Putting the ball squarely in the Palestinian court, US envoy George Mitchell told President Mahmoud Abbas that returning to the table was paramount, chief Palestinian negotiator Saeb Erekat quoted him as saying. Mitchell himself left without comment. Mitchell said that if we want help to achieve a final settlement we must resume the negotiations. This was the main point of discussion, Erekat said. We do not share a common point of view on this issue, he told reporters, blaming the deadlock on the right-wing coalition of Israeli Prime Minister Benjamin Netanyahu, who has refused to stop expanding Jewish settlements around Jerusalem. We want the resumption of negotiations. We are not obstructing negotiations, Erekat said the Palestinians had told Mitchell in the West Bank city of Ramallah on Friday. Therefore you must work with Netanyahu to remove his conditions. Erekat said the Palestinians appreciated the US efforts. But Netanyahu had derailed them, he said. He refused to stop settlement activities, he refused to resume negotiations where we left off, he added, referring to late 2008, when talks with the previous, centrist Israeli government of Ehud Olmert were suspended over the Gaza war. Obama however told Time he still seeks a treaty to end the 62-year-old Middle East conflict and bring peace to the region. We are going to continue to work with both parties to recognise what I think is ultimately their deep-seated interest, he told the magazine. The goal is a two-state solution in which Israel is secure and Palestinians have sovereignty and can start focusing on developing their economy and improving the lives of their children and grandchildren.