President Asif Ali Zardari called for a US change of policy and voiced opposition to missile strikes, as President Barack Obama was to unveil Friday a new strategy against Al-Qaeda. "As far as the question of policy is concerned we have to wait and see that what is the new policy of (the) Obama government towards Balochistan and this region," Zardari told a news conference. He was speaking during a visit to Quetta, which borders Afghanistan and Iran and where an American UN official was kidnapped last month. Obama was Friday to announce a new strategy to "disrupt, dismantle and defeat" Al-Qaeda in safe havens in Afghanistan and Pakistan and deploy an extra 4,000 military trainers. US missile strikes anger many across nuclear-armed Pakistan and the government has warned that they risk a domestic backlash in a country where more than 1,600 people have died in extremist bombings in less than two years.