TOKYO - The United States on Friday issued its most high-level apology yet to Japan over the alleged rape of a woman in Okinawa by two servicemen. US Assistant Secretary of State Kurt Campbell told an audience in Tokyo of Washington’s sorrow, the latest move to soothe anger at a time of heightened anti-US feeling on the island. “I need to begin, if I may, with a heartfelt apology and (the expression of) deep commitment to Japanese friends,” Campbell, the US point man on East Asia, said in a symposium on the Japan-US alliance in Tokyo. “These incidents are profoundly, deeply regrettable and the United States takes them very seriously,” he said.