LONDON - Actress Shannen Doherty, best known for roles in hit TV shows like Beverly Hills 90210 and Charmed, died on Saturday from cancer at 53. “It is with a heavy heart that I confirm the passing of actress Shannen Doherty,” her publicist, Leslie Sloane, said in a statement. “The devoted daughter, sister, aunt and friend was surrounded by her loved ones as well as her dog, Bowie.” Doherty spent over four decades as an actress. She is best known for playing Brenda Walsh on four seasons of 90210. The series followed a group of Beverly Hills teenagers as they faced relationship and family issues. Ms Doherty was nominated for several awards for her role on the show. She later went on to play Brenda in a 2008 reboot of the series where her character grew up to become a theatre actress. The actor was diagnosed with breast cancer in March 2015 and underwent a mastectomy, radiation and chemotherapy. She announced she was in remission in 2017, but the cancer returned two years later. She was open about her battle with cancer, documenting it on social media. In a June 2023 Instagram video, she shared that the the cancer spread to her brain. She announced last fall that she is committed to battling the disease despite it spreading to her bones. “I’m not done with living. I’m not done with loving. I’m not done with creating,” she said to People magazine in November 2023. Born in Memphis, Ms Doherty started acting as a child. She appeared in TV series including Voyagers, Our House and Father Murphy before starring as Jenny Wilder at the age of 11 in Little House on the Prairie. Three years later in 1985, she got her first major film role starring in Girls Just Want to Have Fun, which also starred Sarah Jessica Parker and Helen Hunt. In 1988, Ms Doherty played Heather Duke in the iconic teen film Heathers alongside Winona Ryder, Lisanne Falk and Kim Walker. The actress struggled at the time with being young and famous, earning a reputation as a troublemaker on the set of 90210. “I was very confused back then about what I wanted for myself, and the attention was way too much,” she said.